Last Friday, September 30, the European Night of Research 2022 took place in Plaça Corsini in Tarragona. This event is held every year in more than 300 cities from different European countries, to bring science closer to the population. This scientific dissemination project is promoted by the European Commission in the Horizon 2020 program.

In this year's edition, several members of TecnATox participated on different workshops: Bacteris i el seus misteris, Cervells endollats and Som PLASTICívors! The last one, and a talk on the origins of Alzheimer's disease were also presented in the Fundació "la Caixa" in the CaixaForum of Tarragona.

Finally, we want to thank all the children and adults who attended, for their interest and involvement. It was a very enriching experience for all!
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TecnATox members, coordinators of the SEEDS project, participated in the transnational project meeting organised in a hybrid format, on 29th and 30th of September 2022 in Turin, Italy, with the participation of the representatives of all partner organisations involved in the project. The meeting was an opportunity to review the project progress, to organise the project activities and to assign the last tasks for the remaining period till the end of the project. The SEEDS: Substance of circular Economy concept as Efficacious Determinant for the development of Successful entrepreneurship project (2020-1-ES01-KA202-083137) is Co-Funded by the Erasmus+ Programme of the European Union. More information about the project at:

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Pollution by microplastics is one of the most important environmental problems that humans face right now. In this line, researchers of TecnATox have just published a new article on this topic in the journal Water Research. The study focused on analyzing the concentration, morphology, and composition of microplastics in a drinking water treatment plant located close to Barcelona. The overall removal efficiency of the plant was calculated in more than 98%. According to their estimations, the intake of microplastics through drinking water would not be an important route compared to fish and seafood ingestion.

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Dronjak L, Exposito N, Rovira J, Florencio K, Emiliano P, Corzo B, Schuhmacher M, Valero F, Sierra J. Screening of microplastics in water and sludge lines of a drinking water treatment plant in Catalonia, Spain. Water Res. 2022: 119185

As every year, TecnATox was present in several events of Nit de la Recerca 2022. In the first of them, Dr. Montse Marquès gave a talk at INS Joan Guinjoan (Riudoms), entitled Endocrine disruptors: the chemical cocktail of our everyday life.

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A group of researchers led by Dr. Vikas Kumar has recently published, in collaboration with investigators from IDAEA-CSIC (Barcelona), a new manuscript in the journal NeuroToxicology. This article presents very interesting findings on the effect of 3 pesticides on cell survival, permeability, and tight junction in an in-vitro model of the Human Blood-Brain Barrier. This study was performed in the framework of the Marie Skłodowska-Curie “Neurosome Project”.
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Deepika D, Bravo N, Esplugas R, Capodiferro M, Sharma RP, Schuhmacher M, Grimalt JO, Blanco J, Kumar V. Chlorpyrifos, Permethrin and Cyfluthrin effect on cell survival, permeability, and tight junction in an in-vitro model of the Human Blood-Brain Barrier (BBB). Neurotoxicology 2022

An important delegation of TecnaTox researchers, including Jordina Balaguer, Saurav Kumar, Òscar Sabuz, as well as Dr. Deepika, attended the XVIth International Congress of Toxicology, which was held in the city of Maastricht, the Netherlands, from September 18 to 21, 2022. These researchers presented a number of posters focused on the following areas:

1) Artificial intelligence for predicting BBB permeation
2) In-vitro gut-brain axis along with microbiota for Neurotoxicity
3) In-vitro gut-immune axis along with microbiota for Immunotoxicity
4) Development of PBPK model for organophosphate flame retardant for Neurotoxicity in infants

A PDF copy of the posers presented in the conference can be download here.

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The 34th Annual Conference of the International Society for Environmental Epidemiology / ISEE 2022 took place in September 18-21, 2022, in Athens (Greece). TecnATox was represented by Dr. Montse Marquès, who presented a communication entitled Endocrine disruptors and gestational diabetes mellitus: A pilot study of INSULIN cohort (Catalonia, Spain).

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Researchers of the area of Toxicology have just published a new manuscript in Food and Chemical Toxicology, aimed at assessing social autistic-like behaviors on mice pre or postnatally exposed to chlorpyrifos, in both males and females.
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Biosca-Brull J, Guardia-Escote L, Blanco J, Basaure P, Cabré M, Sánchez-Santed F, Domingo JL, Colomina MT. Prenatal, but not postnatal exposure to chlorpyrifos affects social behavior of mice and the excitatory-inhibitory balance in a sex-dependent manner. Food Chem Toxicol. 2022: 113423

In 2021, Prof. Domingo performed a review of the scientific literature on the origin of SARS-CoV-2 in Environmental Research. One year after, because of the important advances on the knowledge of this virus, he has published an updated review in Environmental Research.

According to the results of the review, the origin of SARS-CoV-2 cannot be not established yet, although most papers point out to a zoonotic origin of this coronavirus. In any case, the hypothesis of an unnatural origin of SARS-CoV-2 cannot be yet scientifically discarded. Imoprtantly, most of the available papers on the origin of SARC-CoV-2 are not experimental studies.

Bibliographic details on this publication can be found below:

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Domingo JL. An updated review of the scientific literature on the origin of SARS-CoV-2. Environ Res. 2022; 215, Part 1: 14131

Experts from all over Europe in research in the fields of toxicology and the environment have gathered in Tarragona to work together within the framework of the European Partnership for the Assessment of Risks from Chemicals (PARC) project, which aims to study the impact that the chemicals present in our environment have on people’s health and to urge governments to improve their regulation.

Chemistry is present in our everyday life (in food, packaging, electronics, clothes…) and also in the air we breathe. It is essential, but so is ensuring that these products are safe for our health and the environment. The TecnATox research group of the Institut d’Investigació Sanitària Pere Virgili (IISPV-CERCA) and the Rovira i Virgili University (URV) has been conducting research in the field of toxicology and the environment for more than 3 decades and it is a reference in Spain.

The European Partnership for the Assessment of Risks from Chemicals (PARC) project is coordinated by the Agence Nationale de Sécurité Sanitaire (ANSES) and nearly 200 key institutions work together in the field of research throughout Europe. In Spain, the Pere Virgili Health Research Institute, which participates in the study as an affiliated entity of the Instituto de Salud Carlos III (ISCIII), is the one that has received the most funds from the European Commission (organization responsible for financing).

PARC is part of the Horizon Europe program, which aims to achieve a scientific, technological, economic and social impact of the European Union’s investments in the field of R&D.

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