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"El naufragi dels records. Què hi ha darrere de malalties com l'Alzheimer?" (The shipwreck of memories. What is behind Alzheimer's disease?) by Dr. Jaume Folch will be presented on April 4 at 7PM in Galatea bookstore (Reus).

This book explains, with an understandable and at the same time rigorous language, why diseases like this deprive us of memories, emotions, affection. It is also about the most surprising theories in the field of neuroscience and reveals the keys to future therapies. We live an extraordinary moment in the search for new treatments for brain disorders that will open a new era for humanity.

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Prof. Francisco García, researcher of the area of Toxicology and medical examiner at the Institute of Legal Medicine and Forensic Sciences of Catalonia, will attend the 22th Scientific Meeting of the Spanish Association of Forensic Doctors and the Legal Medicine School. This meeting will take in March 8th 2019, in the “Centro de Estudios Jurídicos”, Madrid. The conference brings national renowned speakers, as well as the participation of researchers and university students who will present their work and innovations in this field of Forensic Medicine. Dr. García will present the following communications:

Caballero P, García-Sayago F, Soler A, Torralba P, Segú E, Correas C, Landín I, Altés J, Suelves JM, Barbería E. Análisis descriptivo de una serie de muertes por caídas accidentales en mayores de 65 años.

Landín I, Azeli Y, Torralba P,  García-Sayago F, Laguna C, Alvarez R, Bardají A, Barbería E. Incidencia de lesiones óseas y viscerales graves secundarias a RCP: resultado de una serie autópsica.

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Herrero M, Rovira J, Nadal M, Domingo JL. Risk assessment due to dermal exposure of trace elements and indigo dye in jeans: Migration to artificial sweat. Environ Res. 2019 Feb 22;172:310-318. doi: 10.1016/j.envres.2019.02.030.

Sarigiannis DA, Karakitsios S, Dominguez-Romero E, Papadaki K, Brochot C, Kumar V, Schumacher M, Sy M, Mielke H, Greiner M, Mengelers M, Scheringer M. Physiology-based toxicokinetic modelling in the frame of the European Human Biomonitoring Initiative. Environ Res. 2019 Jan 29;172:216-230. doi: 10.1016/j.envres.2019.01.045.

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For a cleaner and healthier air in Kathmandu, The Ministry of Health and Population (MoHP) and World Health Organization (WHO) – Nepal organized “Introductory Training on Health Impact Assessment/Health Economics and Data Analysis Workshop”, a five-day session with 35 representatives from different government agencies working on air quality and related experts, from national and international government organizations, academia, hospitals and representatives from Government of Maldives and WHO offices (HQ, SEARO, India, and Nepal country offices). Dr. Joaquim Rovira, expert in atmospheric pollution of TecnATox, joined the course as a WHO external assessor. You can find more information in the WHO press release.

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Esparza JL, Gómez M, Domingo JL. Role of Melatonin in Aluminum-Related Neurodegenerative Disorders: a Review. Biol Trace Elem Res. 2019 Mar;188(1):60-67.

Schuhmacher M, Mari M, Nadal M, Domingo JL. Concentrations of dioxins and furans in breast milk of women living near a hazardous waste incinerator in Catalonia, Spain. Environ Int. 2019 Feb 7;125:334-341. doi: 10.1016/j.envint.2019.01.074

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María Ángeles Martínez, PhD student of the Health Risk Assessment and Food Toxicology area, attended to the 8th Young Environmental Scientist (YES) Meeting of SETAC. It was celebrated in Ghent (Belgium) from 5th to 10th February 2019.

María Ángeles presented some exciting findings of her thesis in the following poster:

Martínez MA, Rovira J, Kumar V, Schuhmacher M. Tarragona mother-child exposure assessment to wide spread endocrine disruptors (EDs) and in-vitro EDs exposure effects on adipogenesis.

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Schuhmacher M, Mari M, Nadal M, Domingo JL. Concentrations of dioxins and furans in breast milk of women living near a hazardous waste incinerator in Catalonia, Spain. Environ Int. 2019 Apr; 125: 334-341. doi: 10.1016/j.envint.2019.01.074.

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Ferre-Rey G, Sánchez-Rodríguez J, Llorca-Linares M, Vicens P, Camps M, Torrente M, Morales-Vives F. A systematic review of instruments for early detection of autism spectrum disorders. Int J of Psychol Psychol Ther. 2019 Jan; 19, 29-38.

Tomas-Roig J, Torrente M, Cabré M, Vilella E, Colomina MT. Long lasting behavioural effects on cuprizone fed mice after neurotoxicant withdrawal. Behav Brain Res. 2019 May; 363, 38-44. doi: 10.1016/j.bbr.2019.01.036

González N, Marquès M, Nadal M, Domingo JL. Occurrence of environmental pollutants in foodstuffs: A review of organic vs. conventional food. Food Chem Toxicol. 2019 Jan; 125, 370-375. doi:10.1016/j.fct.2019.01.021

Basaure P, Guardia-Escote L, Cabré M, Peris-Sampedro F, Sánchez-Santed F, Domingo JL, Colomina MT. Learning, memory and the expression of cholinergic components in mice are modulated by the pesticide chlorpyrifos depending upon age at exposure and apolipoprotein E (APOE) genotype. Arch Toxicol. 2019 Jan 18. doi: 10.1007/s00204-019-02387-9.

Domínguez-Morueco N, Ratola N, Sierra J, Nadal M, Jiménez-Guerrero P.Combining monitoring and modelling approaches for BaP characterization over a petrochemical area. Sci Total Environ. 2018 Dec 15;658:424-438. doi: 10.1016/j.scitotenv.2018.12.202.

Cabré N, Luciano-Mateo F, Arenas M, Nadal M, Baiges-Gaya G, Hernández-Aguilera A, Fort-Gallifa I, Rodríguez E, Riu F, Camps J, Joven J, Domingo JL. Trace element concentrations in breast cancer patients.Breast. 2018 Oct 1;42:142-149. doi: 10.1016/j.breast.2018.09.005.

Trabalón L, Alves RN, Castro Ó, Nadal M, Borrull F, Pocurull E, Marques A. Preliminary assessment of galaxolide bioaccessibility in raw and cooked fish. Food Chem Toxicol. 2018 Dec;122:33-37. doi: 10.1016/j.fct.2018.09.075.

Crépet A, Vanacker M, Sprong C, de Boer W, Blaznik U, Kennedy M, Anagnostopoulos C, Christodoulou DL, Ruprich J, Rehurkova I, Domingo JL, Hamborg Jensen B, Metruccio F, Moretto A, Jacxsens L, Spanoghe P, Senaeve D, van der Voet H, van Klaveren J. Selecting mixtures on the basis of dietary exposure and hazard data: application to pesticide exposure in the European population in relation to steatosis. Int J Hyg Environ Health. 2018 Dec 19. pii: S1438-4639(18)30548-0. doi: 10.1016/j.ijheh.2018.12.002. [Epub ahead of print]

Rovira J, Domingo JL. Human health risks due to exposure to inorganic and organic chemicals from textiles: A review. Environ Res. 2019 Jan;168:62-69. doi: 10.1016/j.envres.2018.09.027. Epub 2018 Sep 24. Review.

Guardia-Escote L, Basaure P, Blanco J, Cabré M, Pérez-Fernández C, Sánchez-Santed F, Domingo JL, Colomina MT. Postnatal exposure to chlorpyrifos produces long-term effects on spatial memory and the cholinergic system in mice in a sex- and APOE genotype-dependent manner. Food Chem Toxicol. 2018 Dec;122:1-10. doi: 10.1016/j.fct.2018.09.069. Epub 2018 Sep 29.

Suzuki MN, Fregonesi BM, Machado CS, Zagui GS, Kusumota L, Suzuki AK, da Costa JAC, Llopart JS, Nadal M, Domingo JL, Segura-Muñoz S. Hemodialysis Water Parameters as Predisposing Factors for Anemia in Patients in Dialytic Treatment: Application of Mixed Regression Models. Biol Trace Elem Res. 2018 Sep 14. doi: 10.1007/s12011-018-1515-7. [Epub ahead of print]

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González N, Marquès M, Nadal M, Domingo JL. Levels of PCDD/Fs in foodstuffs in Tarragona County (Catalonia, Spain): Spectacular decrease in the dietary intake of PCDD/Fs in the last 20 years. Food Chem Toxicol. 2018 Aug 23. pii: S0278-6915(18)30592-1. doi: 10.1016/j.fct.2018.08.035.

Sharma RP, Schuhmacher M, Kumar V. Development of a human physiologically based pharmacokinetic (PBPK) model for phthalate (DEHP) and its metabolites: A bottom up modeling approach. Toxicol Lett. 2018 Oct 15;296:152-162. doi: 10.1016/j.toxlet.2018.06.1217. Epub 2018 Jun 26.

Antonelli F, Casciati A, Tanori M, Tanno B, Linares-Vidal MV, Serra N, Bellés M, Pannicelli A, Saran A, Pazzaglia S. Alterations in morphology and adult neurogenesis in the dentate Gyrus of Patched1 Heterozygous Mice. Front Mol Neurosci. 2018 May 23;11:168. doi: 10.3389/fnmol.2018.00168. eCollection 2018.

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Prof. Josep Lluís Domingo, Dr. Vikas Kumar, Neus González, María Ángeles MartínezElga Schreiberand Raju P. Sharma are currently to the 54th Congress of the European Societies of Toxicology (EUROTOX 2018), which is held in Brussels (Belgium) from September 2 to 5. They have the following poster presentations:

González N, Marquès M, Nadal M, Domingo JL. Dietary intake of PCDD/Fs by the population of Tarragona County, Catalonia, Spain. Temporal trends (1998-2018).

González N, Schreiber E, Alfageme O, Torrente M, Domingo JL, Gómez M. Assessment of reproductive toxicity of male rats through maternal exposure to dienestrol.

Kumar V, Karri V, Edwin M, Coort S, Evelo C, Oliveira E, Schuhmacher M. A system-based comparative proteomics approach to investigate heavy metals mixtures toxicity mechanism relates to the neurodegeneration on hippocampal cell line.

Martínez MA, Rovira J, Sharma RP, Nadal M, Schuhmacher M, Kumar V. Prediction and evaluation of the internal dosimetry of two wide spread endocrine disruptors in fetus using a physiologically based pharmacokinetic model.

Schreiber E, Garcia T, Torrente M, Kumar V, Sharma RP, Domingo JL, Gómez M. Assessment of the oxidative stress effects on the reproductive system of young male rats to n-butylparaben.

Sharma RP, Kumar V, Schuhmacher M. PBPK/PD coupled HPG SB model to analyze the reproductive toxicity of EDs: case study on mixture effects of DEHP and TCDD.

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