November 2018


Experimental Toxicology
Human health risk assessment
Food Toxicology
Environmental Health

Integrated Life-Cycle and Risk Assessment for Industrial Processes and Products (2nd Edition)

The 2nd Edition of the book "Integrated Life-Cycle and Risk Assessment for Industrial Processes and Products" has been released.

TecnATox has been actively involved in such publication: Prof. Marta Schuhmacher as editor, while Dr. Montse Mari and Dr. Francisco Sánchez-Soberón participated in two different chapters.

Posted on 15-11-2018

Doctoral thesis defense

Roser Esplugas Borràs, PhD candidate in Radiobiology area of TecnATox, will defend her doctoral thesis on 23rd November 2018, at 13.00h in Aula Magna, Faculty of Medicine and Health Science, Universitat Rovira i Virgili.

Title: Efectes del tractament amb radioteràpia en pacients amb càncer de mama. Avaluació in vivo i in vitro de l'expressió dels miARN-146a, -155, -221 i -222 i de la seva associació amb factors de risc cardiovasculars, resposta inflamatòria i disfunció endotelial.

Supervisors: Dr. Montserrat Bellés Mateu, Dr. Victòria Linares Vidal and Dr. Joan Carles Vallvé Torrente.

Posted on 15-11-2018

Doctoral thesis defense

Annabel Folch Mas, PhD candidate co-supervised by Dr. Paloma Vicens Calderón, will defend her doctoral thesis on 16th November 2018, at 11.00h in Pavelló dels Distingits, Institut Pere Mata.

Title: "Disparitats de salut en persones amb transtorns del desenvolupament intel·lectual".

Supervisors: Dr. Paloma Vicens Calderón and Dr. María José Cortés Ruiz.

Posted on 13-11-2018

Last publications of TecnATox

González N, Marquès M, Nadal M, Domingo JL. Levels of PCDD/Fs in foodstuffs in Tarragona County (Catalonia, Spain): Spectacular decrease in the dietary intake of PCDD/Fs in the last 20 years. Food Chem Toxicol. 2018 Aug 23. pii: S0278-6915(18)30592-1. doi: 10.1016/j.fct.2018.08.035.

Sharma RP, Schuhmacher M, Kumar V. Development of a human physiologically based pharmacokinetic (PBPK) model for phthalate (DEHP) and its metabolites: A bottom up modeling approach. Toxicol Lett. 2018 Oct 15;296:152-162. doi: 10.1016/j.toxlet.2018.06.1217. Epub 2018 Jun 26.

Antonelli F, Casciati A, Tanori M, Tanno B, Linares-Vidal MV, Serra N, Bellés M, Pannicelli A, Saran A, Pazzaglia S. Alterations in morphology and adult neurogenesis in the dentate Gyrus of Patched1 Heterozygous Mice. Front Mol Neurosci. 2018 May 23;11:168. doi: 10.3389/fnmol.2018.00168. eCollection 2018.

Posted on 05-09-2018

New publications available in PubMed

Mari M, Rovira J, Sánchez-Soberón F, Nadal M, Schuhmacher M, Domingo JL. Partial replacement of fossil fuels in a cement plant: Assessment of human health risks by metals, metalloids and PCDD/Fs. Environ Res. 2018 Jul 19;167:191-197. doi: 10.1016/j.envres.2018.07.014.

Sakamoto M, Tatsuta N, Chan HM, Domingo JL, Murata K, Nakai K. Brain methylmercury uptake in fetal, neonate, weanling, and adult rats. Environ Res. 2018 Jul 5;167:15-20. doi: 10.1016/j.envres.2018.06.038.

Posted on 16-07-2018

TecnATox in the Congress of the European Societies of Toxicology

Prof. Josep Lluís Domingo, Dr. Vikas Kumar, Neus González, María Ángeles Martínez, Elga Schreiber and Raju P. Sharma are currently to the 54th Congress of the European Societies of Toxicology (EUROTOX 2018), which is held in Brussels (Belgium) from September 2 to 5. They have the following poster presentations:

González N, Marquès M, Nadal M, Domingo JL. Dietary intake of PCDD/Fs by the population of Tarragona County, Catalonia, Spain. Temporal trends (1998-2018).

González N, Schreiber E, Alfageme O, Torrente M, Domingo JL, Gómez M. Assessment of reproductive toxicity of male rats through maternal exposure to dienestrol.

Kumar V, Karri V, Edwin M, Coort S, Evelo C, Oliveira E, Schuhmacher M. A system-based comparative proteomics approach to investigate heavy metals mixtures toxicity mechanism relates to the neurodegeneration on hippocampal cell line.

Martínez MA, Rovira J, Sharma RP, Nadal M, Schuhmacher M, Kumar V. Prediction and evaluation of the internal dosimetry of two wide spread endocrine disruptors in fetus using a physiologically based pharmacokinetic model.

Schreiber E, Garcia T, Torrente M, Kumar V, Sharma RP, Domingo JL, Gómez M. Assessment of the oxidative stress effects on the reproductive system of young male rats to n-butylparaben.

Sharma RP, Kumar V, Schuhmacher M. PBPK/PD coupled HPG SB model to analyze the reproductive toxicity of EDs: case study on mixture effects of DEHP and TCDD.

Posted on 05-09-2018

TecnATox in the European Radiation Research Congress

Roser Esplugas, PhD candiate in the Radiobiology area, will attend to the 44th European Radiation Research Congress (ERR 2018). It will be held in Pécs (Hungary) from August 21 to 25, 2018. She will be presenting the following posters:

Roser Esplugas, Noemí Serra, Montserrat Bellés, Victoria Linares, Meritxell Arenas, Joan Carles Vallvé. Effect of 2 Gy-radiation on the expression of miRNAs-146a, -155, -221 and -222 in HUVECs.

Roser Esplugas, Noemí Serra, Montserrat Bellés, Victoria Linares, Meritxell Arenas, Joan Carles Vallvé. Effect of radiotherapy, molecular parameters and treatment on the expression of blood miRNAs-146a, -155, -221 and -222 in women with breast cancer.

Posted on 31-07-2018

TecnATox in betevé

Prof. Josep Lluís Domingo has recently been interviewed in betevé. He talked about the high concentrations of dioxins reported in the surroundings of the municipal waste incinerator located in Sant Adrià del Besos (Barcelona). He asks for immediate measures to reduce the emissions of dioxins in the aforementioned facility, which were found up to 2.3 times the acceptable threshold.

You can watch the full interview in the following link.

Posted on 11-07-2018